Chitosan Fiber Made From 100% Chitosan Is Used for Medical Purposes for Wound Dressing for Chitosan Fabric and for Chitosan Hemostatic Gauze

• Customization: Available
• Usage: Non-Woven Fabric
• Material: 100% Pure Chitosan Fiber
• Model NO.: 100% Pure Chitosan Fiber
• Fiber Type: 100% Pure Chitosan Fiber
• Pattern: Plain
• Color: White
• Width: According to Client′s Request
• Function: Medical Clothing Textiles and Home Textiles
• Composition: Chitosan
• Advantages: Anti-Static, Flame Retardant ,Antibacteria
• Certificate: ISO13485
• Use: for Medical Purposes for Wound Dressing
• CAS Number: 9012-76-4
• Application: Rapid Hemostasis Prevent Adhesion
• Functions: Promote Healing Effective Bacteriostasis Absorbabl
• Transport Package: Suit for The Exporting Packaging
• Specification: according to client′s request
• Trademark: yaliya
• Origin: China
• HS Code: 55049000
• Production Capacity: 100mt/Month

Product Description

Product Description
100% pure Chitosan Fiber 

Chitosan is the only polymer material with positive charge in nature, which has the characteristics of natural bacteriostasis, promoting healing and regeneration, strengthening immunity, and adsorption protection, etc. The degree of deacetylation of pure chitosan fiber in our company is over 92%, and the cytotoxicity is not greater than level 1, which ensures the bacteriostasis and stability of the product.

Based on the function of chitosan fiber, it can be widely used in high-grade dressing and gauze in medical field.Functional underwear and antibacterial yarn in textile field;Health field functional mask, wet towel, sanitary napkin, baby diapers, etc.

Naturally Anti-Bacterial
Promoting healing and regeneration
Strengthening immunity
Adsorption protection

Chitosan - based absorbable hemostatic nonwoven fabric
Main component: Carboxymethyl chitosan
Characteristics: White or light yellow nonwoven, uniform, soft, absorbable hemostatic material, sterile
Scope of application: It is used to control bleeding in capillaries, veins and arterioles during surgery when ligation or other conventional methods are not applicable or ineffective.
Size:20mm*20mm-50mm*100mm or etc.
Five functions:1, Rapid hemostasis 2, Prevent adhesion 3,Promote healing 4,Effective bacteriostasis 5,absorbable

Prevent adhesion:
(1) High viscoelastic colloid is formed on the surgical wound to form a physical barrier between it and normal tissue to effectively prevent adhesion;
(2) Effective hemostasis, reduce hematoma mechanization and fibroblast invasion, play a role in preventing adhesion.

Effective bacteriostasis:
Carboxymethyl chitosan inhibits metabolism and reproduction by changing the permeability of microbial cell membrane and entering the internal flocculating organelles.

Rapid hemostasis

(1) The high viscoelastic gel network structure can effectively physically seal the broken end of blood vessels;
(2) The effect of electric charge can activate the aggregation of blood cells, can adhere to platelets, and promote coagulation factors to initiate coagulation.

Promote healing
Carboxymethyl chitosan can promote the growth of normal fibroblasts.

Completely degradable
Complete degradation in 7-10 days


Effect 1: Quick hemostasis
Physical aggregation: After contact with blood, the non-woven form is transformed into a high viscoelastic gel, which is closely attached to the wound and effectively physically occludes the bleeding wound to achieve rapid hemostasis.
Charge aggregation: Chitosan cation aggregates red blood cells through charge, adheres to platelets, promotes the release of coagulation factors, and thus stops bleeding.

Aggregation of red blood cells in vitro.
The component of the yarn, carboxymethyl chitosan, is the only positively charged substance in the biological material, which can trap red blood cells to aggregate and form blood clots.

An open wound (5mmx3mmx2mm) was created in the left lobe of the rat liver to form a bleeding model. The experimental group applied Zhuyi yarn to the wound, and the control group applied yarn as quickly as possible. The hemostatic time and total blood loss (TBL) were recorded.
The experimental results showed that the hemostasis time of the experimental group was shorter than that of the control group, and the TBL was also smaller.

Efficacy 2: Prevent adhesion
Carboxymethyl chitosan did not increase the collagen secretion level of fibroblasts.
At 24h and 48h, different concentrations of L-CMC did not increase the secretion of hydroxyproline from fibroblasts.
Within 72h, 100μg/ml L-CMC did not increase hydroxyproline secretion.
Carboxymethyl chitosan significantly increased the value of matrix metalloproteinase 1 (MMP-1).

The effect of anti-adhesion in SD rats was evaluated by anatomy in a 1cm*2cm abrasions model of the abdominal wall in the middle and lower abdomen.
The high adhesion ratio of carboxymethyl chitosan group was lower than that of other groups, indicating better ability to prevent postoperative adhesion.

Effect 3: Effective bacteriostasis
Carboxymethyl chitosan in high concentration can inhibit many kinds of bacteria.
Bacteriostatic results of carboxymethyl chitosan of different concentrations with molecular weight 6.6*104.
Bacteriostatic results of carboxymethyl chitosan with different concentrations of molecular weight 0.5*104.

Effect 4: significant analgesia
Carboxymethyl chitosan can inhibit the production of inflammatory factors in the blood

Effects of chitosan and carboxymethyl chitosan on the content of vascular soothing kinin in rat scald model

Effects of chitosan and carboxymethyl chitosan on the content of 5-hydroxytryptamine in blood of rat scalded model

Effect five: degradable absorption
Carboxymethyl chitosan degradation products are safe and non-toxic.
In the in vivo degradation and absorption test, the inflammation of Zhuyisha ® after 2 weeks implantation was grade 0, and the sample degradation was complete, which met the relevant requirements.

Usage and precautions
Usage method
1. Aseptic packaging, open the inner packaging can be used;
2. This product can be bent and cut into different shapes at will, suitable for irregular tissue wounds;
3. After the bleeding wound is clear, put this product on the bleeding wound and apply the gauze closely to the wound;
4. The bleeding wound does not need to be clean, it can be directly covered.

Matters needing attention
1. Should be strictly aseptic operation, do not use when the package is damaged;
2. Intraspinal indentation is not recommended during spinal surgery.
3. For orthopedic surgery, the bone marrow cavity should be avoided and not in contact with bone cement;
4. When using this product under endoscope, keep the instrument dry, roll the yarn into a roll and send it into the body cavity through Chowka.